Polynucleotides

Polynucleotide Treatments in Kent, Essex and London

MAXIMUM RESULTS | REJUVENATING | COLLAGEN STIMULATING | ANTI-AGEING | £300

Polynucleotide Treatment

Advanced Regenerative Skin Rejuvenation

If you have heard the terms ‘Salmon DNA facials’ or ‘Bio-stimulators’ discussed within anti-ageing treatments, then you’ve found the right page! ‘Polynucleotides’ are a next-generation injectable treatment designed to improve skin quality at a deeper cellular level. Rather than adding volume or changing facial contours as can be done with dermal fillers, this advanced regenerative therapy stimulates your skin to repair, hydrate and strengthen itself from within.

For Intrigue Cosmetic Clinic clients seeking refined, natural results and long-term skin optimisation, polynucleotides offer a clinically driven solution grounded in regenerative science.

What Are Polynucleotides?

Polynucleotides are highly purified DNA fragments, most commonly derived from salmon or trout due to their strong biocompatibility with human tissue. When precisely injected into the skin, they act as powerful bio-stimulators.

Unlike dermal fillers, polynucleotides do not “fill” lines or reshape the face. Instead, they improve the condition of the skin itself by:

• Stimulating fibroblast activity
• Increasing collagen and elastin production
• Improving deep dermal hydration
• Supporting tissue repair
• Decreasing oxidative stress and inflammation

The result is healthier, more resilient skin without an altered appearance.

Why Polynucleotides Work

Polynucleotides activate the body’s natural regenerative processes in a number of ways:

1. Collagen & Elastin Stimulation
They encourage fibroblasts (the cells that produce collagen and elastin) to increase their activity. Over time, this improves firmness, elasticity and structural strength.

2. Deep Skin Hydration
Polynucleotides attract and bind water molecules within the dermis, delivering hydration from within rather than sitting superficially on the skin.

3. Tissue Repair & Healing
By enhancing microcirculation and cellular turnover, Polynucleotides are especially effective for fragile, damaged or ageing skin.

4. Anti-Inflammatory & Antioxidant Support
Their antioxidant properties help to soothe inflammation while protecting against environmental stressors that accelerate the ageing process.

This multi-layered regenerative effect is why polynucleotides are increasingly used in preventive and corrective aesthetics at our Gravesend beauty clinic to deliver the best results and outcomes for our clients.

Best Treatment Areas

Polynucleotide injections can be used across multiple areas where skin quality improvement is required. These can include:

• Under-eye area (fine lines, crepey skin, dark circles)
• Full face (texture, laxity, dullness)
• Neck
• Décolletage
• Hands
• Acne scarring
• Post-inflammatory skin damage

They are particularly well-suited to more delicate areas and where dermal fillers may be an unsuitable choice for an individual client.

Who Is Polynucleotide Treatment For?

Polynucleotides are ideal for individuals who want to:

• Improve early signs of ageing
• Address fine lines and skin laxity
• Restore hydration and radiance
• Improve under-eye quality without adding volume
• Strengthen fragile or thinning skin
• Support long-term skin health

Suitable for both men and women, this treatment can be used preventatively in younger patients or restoratively in more mature skin.

What to Expect

Treatment takes approximately 30–45 minutes. A topical anaesthetic may be applied for comfort.

For best results, a course of 2–3 sessions spaced 2–4 weeks apart is recommended. Maintenance treatments may be advised every 6–12 months, depending on individual skin goals.

Mild swelling, redness, or small injection-site bumps may occur and typically resolve within 24–72 hours. Downtime is minimal, and most patients resume normal activities shortly after treatment.

Results develop gradually as collagen production increases. Improvements in hydration may be noticeable within a few weeks, with continued skin strengthening over several months.

Benefits of Polynucleotides

• Stimulates collagen production
• Improves skin firmness and elasticity
• Boosts deep dermal hydration
• Refines skin texture for a more youthful appearance
• Brightens the under-eye area
• Strengthens thin or fragile skin
• Promotes long-term skin regeneration
• Gives natural, subtle results
• Offers minimal downtime

Polynucleotides vs Dermal Fillers

Although often compared, polynucleotides and dermal fillers serve different purposes.

• Polynucleotides focus on improving skin quality by stimulating regeneration. Results develop gradually and enhance the integrity of the skin itself.
• Dermal fillers are designed to restore lost volume or reshape facial contours, delivering instant structural change.

Many patients benefit from a combined approach, harnessing the volumising and contouring benefits of dermal fillers with this regenerative treatment to enhance skin quality while addressing volume loss.

Frequently Asked Questions

How long do polynucleotides last?

After a full course of treatment, results typically last between 6 and 12 months. Longevity depends on skin condition, lifestyle and maintenance.

Are polynucleotides safe?

Yes. When administered by a qualified medical professional, polynucleotide injections have an excellent safety profile. They are highly purified and biocompatible.

Do polynucleotide injections hurt?

Most patients experience mild discomfort only. A topical numbing cream can be applied before treatment to improve comfort.

When will I see results?

Hydration improvements may be visible within 2–3 weeks. Collagen stimulation and tightening effects are more noticeable from 4–8 weeks onward.

Can polynucleotides be used under the eyes?

Yes. This is one of their most popular applications. They improve fine lines, crepey texture and dark circles without creating puffiness.

Is there any downtime?

Minor swelling or small injection marks may last 1–3 days. Significant downtime is uncommon.

Can I combine polynucleotides with other treatments?

Yes. Polynucleotides work well alongside microneedling, skin boosters, anti-wrinkle injections and dermal fillers as part of a comprehensive skin rejuvenation plan.

Why Choose Our Clinic for Skin Rejuvenation?

• Medically trained aesthetics practitioners
• Premium injectable products
• Bespoke treatment protocols
• Evidence-based approach
• UK-compliant clinical environment
• Focus on natural, healthy skin outcomes

If you’re ready for smoother, brighter, deeply hydrated skin, book a personalised consultation with us today. Skin boosters offer a refined, science-led approach to modern skin rejuvenation while delivering healthy radiance from within.